Michael Jai White

Character: Al Simmons / Spawn

Martin Sheen

Character: Jason Wynn

John Leguizamo

Character: Clown / Violator

Theresa Randle

Character: Wanda Blake

Nicol Williamson

Character: Cogliostro

D. B. Sweeney

Character: Terry Fitzgerald

Melinda Clarke

Character: Jessica Priest

Miko Hughes

Character: Zack

Sydni Beaudoin

Character: Cyan

Michael Papajohn

Character: Glen, Zack's Dad

Frank Welker

Character: The Devil Malebolgia (voice)

Tony Haney

Character: African Liaison

Todd McFarlane

Character: Bum

Simon Rhee

Character: Hong Kong Military Air Base Person (uncredited)

Robia LaMorte

Character: XNN Reporter

John Cothran

Character: African Liaison

Caroline Gibson

Character: News Anchor

Marc Robinson

Character: Punk #1

Chris Coppola

Character: Punk #2

Jay Caputo

Character: Punk #3

Darryl Warren

Character: Security Guard

Mike Akrawi

Character: Foreign Dignitary #1

Romeo Akrawi

Character: Foreign Dignitary #2

Jack Coleman

Character: Doctor

Laura Interval

Character: Angela (as Laura Stepp)

Garrison M. Singer

Character: Anesthesiologist

John Koyama

Character: Hong Kong Military Air Base Security (uncredited)

Al Goto

Character: Hong Kong Military Air Base Person (uncredited)

Roger Yuan

Character: Korean Soldier (uncredited)

Angelie Almendare

Character: Diplomat's Wife (uncredited)