Andy García

Character: Michael Green

Meg Ryan

Character: Alice Green

Tina Majorino

Character: Jessica Green

Philip Seymour Hoffman

Character: Gary

Mae Whitman

Character: Casey Green

Ellen Burstyn

Character: Emily

Eugene Roche

Character: Walter

Gail Strickland

Character: Pam

Susanna Thompson

Character: Janet

Lauren Tom

Character: Amy

Steven Brill

Character: Madras Tie Guy

Erinn Canavan

Character: Shannon

LaTanya Richardson Jackson

Character: Dr. Gina Mendez

Bari K. Willerford

Character: Malcolm

James Jude Courtney

Character: Earl

Jacques De Groot

Character: Guy in the Back

Anne Ohliger

Character: Jess - 4 Yrs. Old

Tony Montero

Character: Bartender

Cynthia Mace

Character: De-tox Nurse

Jennie Yee

Character: Vu

William Frankfather

Character: Al-anon Leader

Ellen Geer

Character: Woman at Al-Anon

Angelina Fiordellisi

Character: Joanna

Elizabeth Lang

Character: AA Woman

Syd Field

Character: Patient #1

Peer Ebbighausen

Character: Patient #2

Ronald Bass

Character: AA Man #1

Joe Drago

Character: AA Man #2

Andrew Magarian

Character: AA Man #3

Amy Treese

Character: AA Woman #2

Brandis Kemp

Character: AA Woman #3

Judith Friend

Character: AA Woman #4

Deana Kobrynski

Character: AA Woman #5

Rico E. Anderson

Character: Barfly (uncredited)

Lena Banks

Character: Nurse (uncredited)

Richard Bradford

Character: Angry Man Watching TV (uncredited)

Al Franken

Character: Co-Pilot (uncredited)

Craig Richards

Character: Patient #3 (uncredited)

Reed Rudy

Character: Angry Guy (uncredited)

Joseph Quinn Simpkins

Character: Barfly (uncredited)