Anthony Hopkins

Character: Dr. John Harvey Kellogg

Bridget Fonda

Character: Eleanor Lightbody

Matthew Broderick

Character: William Lightbody

John Cusack

Character: Charles Ossining

Dana Carvey

Character: George Kellogg

Michael Lerner

Character: Goodloe Bender

Colm Meaney

Character: Dr. Lionel Badger

John Neville

Character: Endymion Hart-Jones

Lara Flynn Boyle

Character: Ida Muntz

Traci Lind

Character: Nurse Irene Graves

Camryn Manheim

Character: Virginia Cranehill

Roy Brocksmith

Character: Poultney Dab

Norbert Weisser

Character: Dr. Spitzvogel

Monica Parker

Character: Mrs. Tindermarsh

Jacob Reynolds

Character: Young George Kellogg

Michael Goodwin

Character: Dr. Frank Linniman

Marshall Efron

Character: Bartholomew Bookbinder

Aleksandr Slanksnis

Character: Mr. Unpronounceable

Carole Shelley

Character: Mrs. Hookstratten

Gabriel Barre

Character: Desk Clerk

Robert Tracey

Character: Ernest O'Reilly

Ann Tucker

Character: Hannah

Jemila Ericson

Character: Mrs. Kellogg

Marianne Muellerleile

Character: Nurse Bloethal

Jean Wenderlich

Character: Ralph

Mark Jeffrey Miller

Character: Woodbine

Joanne Pankow

Character: Laughing Lady

Mary Jane Corry

Character: Pianist

Rich Valliere

Character: Reporter #1

George Nannarello

Character: Reporter #2

James Bigwood

Character: Reporter #3

David Kraus

Character: Laughing Instructor

D. Anthony Pender

Character: Waiter on Train

Mary Lucy Bivins

Character: Woman on Train

William Hempel

Character: Bellman

Richard H. Thornton

Character: Mr. Abernathy

Lisa Altomare

Character: Mrs. Portois

Jim Bath

Character: Bartender

Madeline Shaw

Character: Waitress #1

Barbara Phillips

Character: Waitress #2

Lindsay Hutchinson Berte

Character: Breathing Instructor

Denise S. Bass

Character: Nurse

Charlotte H. Ballinger

Character: San Guest

John Henry Scott

Character: Bath Attendant

Richard K. Olsen

Character: Fox Fur Man

Ann Deagon

Character: Fox Fur Woman

Thomas Myers Jr.

Character: Process Server

Beth Bostic

Character: Miss Jarvis

Kerry Maher

Character: Doorman

Sam Garner

Character: Farrington