John Getz

Character: Ray

Frances McDormand

Character: Abby

Dan Hedaya

Character: Julian Marty

Samm-Art Williams

Character: Meurice

M. Emmet Walsh

Character: Private Detective

Deborah Neumann

Character: Debra

Raquel Gavia

Character: Landlady

Van Brooks

Character: Man from Lubbock

Señor Marco

Character: Mr. Garcia

William Creamer

Character: Old Cracker

Loren Bivens

Character: Strip Bar Exhorter

Bob McAdams

Character: Strip Bar Senator

Shannon Sedwick

Character: Stripper

Nancy Finger

Character: Girl on Overlook

William Preston Robertson

Character: Radio Evangelist (voice)

Holly Hunter

Character: Helene Trend (voice) (uncredited)

Barry Sonnenfeld

Character: Marty's Vomiting (voice) (uncredited)