Colin Farrell

Character: Captain Smith

Q'orianka Kilcher

Character: Pocahontas

Christopher Plummer

Character: Captain Newport

Christian Bale

Character: John Rolfe

August Schellenberg

Character: Powhatan

Wes Studi

Character: Opechancanough

David Thewlis

Character: Wingfield

Yorick van Wageningen

Character: Captain Argall

Raoul Max Trujillo

Character: Tomocomo

Michael Greyeyes

Character: Rupwew

Kalani Queypo

Character: Parahunt

Ben Mendelsohn

Character: Ben

Noah Taylor

Character: Selway

Brían F. O'Byrne

Character: Lewes

Ben Chaplin

Character: Robinson

Jamie Harris

Character: Emery

Janine Duvitski

Character: Mary

Eddie Marsan

Character: Eddie

Joe Inscoe

Character: Ackley

Jake Curran

Character: James

John Savage

Character: Savage

Thomas Clair

Character: Patawomeck

Alex Rice

Character: Patowomeck's Wife

Irene Bedard

Character: Pocahontas' Mother

Ford Flannagan

Character: Winthrop

Bev Appleton

Character: Small

Billy Merasty

Character: Kiskiak

Jonathan Pryce

Character: King James

Alexandra W.B. Malick

Character: Queen Anne

Jasper Britton

Character: Laureate

Myrton Running Wolf

Character: Tockwhogh

E. Danny Murphy

Character: Bosun

Jonathan Gonitel

Character: Thomas - 4 Yrs

Brian Merrick

Character: Assailant

Chris Nelson

Character: Chris

Colin Cox

Character: Cox

Will Wallace

Character: William Sentry

Steven Dawn

Character: Goldsmith

Rulan Tangen

Character: Two Moons

Jesse Borrego

Character: Pepaschicher

Todd Wallace

Character: Sailor

Kirk Acevedo

Character: Sentry

Nive Nielsen

Character: Inuit Woman

Tayla Kean

Character: Cabin Boy 1

Thomas Steven McDonagh

Character: Cabin Boy 2

James McDonagh

Character: Cabin Boy 3

Gary Sundown

Character: Messenger

Michael Goodwin

Character: Helmsman

Sam Stevenson

Character: Young Lady

Maria Pastel

Character: Rosalind

Raynor Scheine

Character: Raynor

Jeremy Radin

Character: Jeremy

Matthew Yeung

Character: Shaman

Gregory Labenz

Character: Sentry 2

Miraida Rios

Character: (voice actor)