Michael Angarano

Character: Will Stronghold

Mary Elizabeth Winstead

Character: Gwen Grayson / Royal Pain

Kurt Russell

Character: Steve Stronghold / The Commander

Kelly Preston

Character: Josie Stronghold / Jetstream

Danielle Panabaker

Character: Layla Williams

Bruce Campbell

Character: Coach Boomer

Lynda Carter

Character: Principal Powers

Kevin Heffernan

Character: Ron Wilson, Bus Driver

Dee Jay Daniels

Character: Ethan

Kelly Vitz

Character: Magenta

Loren Berman

Character: Little Larry

Nicholas Braun

Character: Zachary "Zach" Braun / Zack Attack

Steven Strait

Character: Warren Peace

Malika

Character: Penny

Khadijah Haqq McCray

Character: Penny

Jake Sandvig

Character: Lash

Will Harris

Character: Speed

Dustin Ingram

Character: Carbon Copy Kid

Christopher Wynne

Character: News Anchor

Cloris Leachman

Character: Nurse Spex

Jim Rash

Character: Mr. Grayson / Stitches

Dave Foley

Character: Mr. Boy

Kevin McDonald

Character: Mr. Medulla

Amy Brown

Character: Twin

Kimmy Brown

Character: Evil Twin

Lucille Soong

Character: Cook

Zachry Rogers

Character: Young Commander

Tom Kenny

Character: Mr. Timmerman

Jill Talley

Character: Mrs. Timmerman

Patrick Warburton

Character: Royal Pain (voice)

Vakisha Coleman

Character: Student Sidekick (uncredited)

Sean Gordon

Character: Penny's Date (uncredited)

Hans Hernke

Character: Laser-Vision Boy (uncredited)

Jason Maxim

Character: Funky Prom Boy (uncredited)