Gary Cooper

Character: Marco Polo

Sigrid Gurie

Character: Princess Kukachin

Basil Rathbone

Character: Ahmed

George Barbier

Character: Kublai Khan

Binnie Barnes

Character: Nazama

Ernest Truex

Character: Binguccio

Alan Hale

Character: Kaidu

H.B. Warner

Character: Chen Tsu

Robert Greig

Character: Chamberlain

Ferdinand Gottschalk

Character: Persian Ambassador

Henry Kolker

Character: Nicolo Polo

Lotus Liu

Character: Visakha

Stanley Fields

Character: Bayan

Harold Huber

Character: Toctai

Lana Turner

Character: Maid

Ward Bond

Character: Mongol Guard (uncredited)

Richard Farnsworth

Character: Mongol Warrior (uncredited)

Hale Hamilton

Character: Maffeo Polo (uncredited)

Theodore von Eltz

Character: Venetian Business Man (uncredited)