Michael Douglas

Character: Dr. Nathan Conrad

Sean Bean

Character: Patrick Koster

Brittany Murphy

Character: Elisabeth Burrows

Skye McCole Bartusiak

Character: Jessie Conrad

Guy Torry

Character: Dolen

Jennifer Esposito

Character: Det. Sandra Cassidy

Famke Janssen

Character: Aggie Conrad

Oliver Platt

Character: Dr. Louis Sachs

Shawn Doyle

Character: Russel Maddox

Victor Argo

Character: Sydney Simon

Conrad Goode

Character: Max Dunlevy

Paul Schulze

Character: Jake

Lance Reddick

Character: Arnie

Aidan Devine

Character: Leon Edward Croft

Alex Campbell

Character: Jonathan

Philip DeWilde

Character: Intern

Sam Montesano

Character: Frankie

Arlene Duncan

Character: Aide

Judy Sinclair

Character: Zelda Sinclair

Larry Block

Character: Doorman

David Warshofsky

Character: Ryan

Darren Frost

Character: Janitor

Philip Williams

Character: Large Cop

Louis Vanaria

Character: Cop at Scene

Daniel Kash

Character: Detective Garcia

Lucie Laurier

Character: Vanessa

Isabella Fink

Character: 8-Year-Old Elisabeth

Ray Iannicelli

Character: Man at Marina

Colm Magner

Character: Cop #1

Cyrus Farmer

Character: Officer #1

Martin Roach

Character: Transit Cop

Patricia Mauceri

Character: Sofia

Tony Bruno

Character: Radio Host (uncredited)

Paul J.Q. Lee

Character: Man with a Cell Phone (uncredited)

Lorli Villanueva

Character: Chinese Woman (uncredited)