Matthew Broderick

Character: Taylor Peters

Brittany Snow

Character: Amanda

Maura Tierney

Character: Lorraine Mendon

Peter Facinelli

Character: Greg

Steve Coogan

Character: Michael Henry

Ed Begley Jr.

Character: Self

Bill Fagerbakke

Character: Larry

Patrick Fischler

Character: Kevin - TV Executive

Daniel Roebuck

Character: Link

Lester Speight

Character: BV

J. P. Manoux

Character: Tony Clark

Katy Mixon

Character: Girl #1 with Greg

Peggy J. Scott

Character: Sharon the Maid

Jennifer Rau

Character: Whisper

Allan Wasserman

Character: Dr. Chase

Jenni Blong

Character: Paula

Signe Kiesel

Character: Dealer at Casino

Allie McCulloch

Character: Eve

Anthony Holiday

Character: Arco

Atticus Todd

Character: Gene

Victoria De Mare

Character: Hot Club Goer #1 (uncredited)

Sean T. James

Character: Insulting John (uncredited)

Kate Micucci

Character: Thin Girl (uncredited)

Vitta Quinn

Character: Vegas Hooker (uncredited)

Michael Proctor

Character: Hot Guy (uncredited)