David Cross

Character: Ronnie Dobbs / Pootie T / Chow Chow

Bob Odenkirk

Character: Terry Twillstein / Wolfgang Amadeus Thelonius Von Funkenmeister the XIX 3 / 4 / Daffy Mal Yinkle Yankle

Bruce Taylor

Character: Dot Lancaster

Leon Lamar

Character: Tammy's Neighbor

India Cosper

Character: Middle Ronnie

Blaze Walker

Character: Little Middle Ronnie

Storm Walker

Character: Little Ronnie

Jill Talley

Character: Tammy

Paul Carden

Character: Tas-Tee Liquor Store Owner

Becky Thyre

Character: Tonya

Suli McCullough

Character: Kyle

David Koechner

Character: Clay

Saucy

Character: F'd Up Dog

E.J. De la Pena

Character: Jerry Trellis

Jonathon Pelletier

Character: 9 Year Old Ronnie

Kimberly Schwartz

Character: 9 Year Old Tammy

Matthew Draper

Character: 12 Year Old Ronnie

Amber Brooke

Character: 12 Year Old Tammy

M.C. Gainey

Character: Hark Trellis

Frank Hoyt Taylor

Character: Frank - 'Fuzz' Cop

Bill Rowell

Character: Bill - 'Fuzz' Cop

Pearlyne Irving

Character: Darnetta

Shawn Maurer

Character: 'Fuzz' Cameraman

Tommy Smeltzer

Character: Police Station Guard

Brett Paesel

Character: Infomercial Nancy

Brian Posehn

Character: Tank

Patton Oswalt

Character: Dozer - Editor #1

Donna Wright

Character: Undercover Hooker

Ken Daly

Character: Editor #2

Doug Benson

Character: Editor #3

Dean Holland

Character: Editor #4

John Matta

Character: Editor #5

Blaine Cartwright

Character: Duke's Bar Owner

Ted Manson

Character: Oldie Bowling Alley Man

Kenny Alfonso

Character: High School Cop

Greg Behrendt

Character: Radio DJ 'The Lemur'

Dave Foley

Character: Network Executive #1

Andy Richter

Character: Network Executive #2

Sarah Silverman

Character: Network Executive #3

Trey Parker

Character: Self

Matt Stone

Character: Self

Rebecca Romijn

Character: Self

John Stamos

Character: Self

Colin Malone

Character: Self

Garry Shandling

Character: Self

Scott Ian

Character: Self

Kathy Griffin

Character: Self

Craig Anton

Character: Holywood Agent

Laura Kightlinger

Character: Birthday Woman

Jeff Garlin

Character: Birthday Woman's Friend

Christopher Nguyen

Character: Chow Chow

John Andrews

Character: Party Photographer

Drew McWeeny

Character: Self

Scott Thompson

Character: Self

Patrick Warburton

Character: Head of Gay Conspiracy

Nikki Cox

Character: Kayla

Elisha Choice

Character: Music Video

Tom Kenny

Character: TV News Reporter / Cult Leader Gleh'n

Paul F. Tompkins

Character: Safari Guy in TV

Wendy Cross

Character: Terry's NYC Assistant

Mandy Patinkin

Character: Self

Cookie Brindle

Character: Terry's NYC Assistant #1

Mary Lynn Rajskub

Character: Self

Jim Turner

Character: Self

Jack Black

Character: Lead Chimney Sweep

Scott Adsit

Character: Police Negotiator

R. Lee Ermey

Character: Lead Kidnapper

Scott Aukerman

Character: Starving Kidnapper

Lance Bangs

Character: Gay Conspiracy Technician

Jeff Goldblum

Character: Self

Maynard James Keenan

Character: Titannica Lead Singer

Jim Norton

Character: Cop

Kulap Vilaysack

Character: Gay Female Military Type #2

Morwenna Banks

Character: British Couple

Zia Harris

Character: Cult Member Gr'hg

Ben Stiller

Character: Self

Bill Crabb

Character: Prison Guard