Jeff Bridges

Character: Dr. Mark Powell

Kevin Spacey

Character: Prot

Mary McCormack

Character: Rachel Powell

Alfre Woodard

Character: Claudia Villars

Ajay Naidu

Character: Dr. Chakaraborty

Vincent Laresca

Character: Navarro

Kimberly Scott

Character: Joyce Trexler

Conchata Ferrell

Character: Betty McAllister

Saul Williams

Character: Ernie

Peter Gerety

Character: Sal

David Patrick Kelly

Character: Howie

Melanee Murray

Character: Bess

Celia Weston

Character: Mrs. Archer

Brian Howe

Character: Steve Becker

Greg Lewis

Character: Dominic McAllister

John Toles-Bey

Character: Russell

Mark Christopher Lawrence

Character: Simms

Mary Mara

Character: Abby

Brandon de Paul

Character: Josh - Age 10

Tess McCarthy

Character: Natalie Powell - Age 6

Natasha Dorfhuber

Character: Gabby Powell - Age 9

Aaron Paul

Character: Michael Powell - Age 21

William Lucking

Character: Sheriff

Zofia Borucka

Character: Woman on Train

Curt Clendenin

Character: Hospital Patient (uncredited)

Frank Collison

Character: Screaming Man (uncredited)

Moet Meira

Character: Jennifer (uncredited)

Peter Maloney

Character: Duncan Flynn

Lance E. Nichols

Character: David Patel

Erik LaRay Harvey

Character: Security Guard

Paulo Pascoal

Character: Thief (Uncredited)

Tracy Vilar

Character: Maria