Basil Rathbone

Character: Sherlock Holmes

Nigel Bruce

Character: Dr. Watson

Ida Lupino

Character: Ann Brandon

Alan Marshal

Character: Jerrold Hunter

Terry Kilburn

Character: Billy

George Zucco

Character: Professor Moriarty

Henry Stephenson

Character: Sir Ronald Ramsgate

E. E. Clive

Character: Inspector Bristol

Arthur Hohl

Character: Henchman Bassick

May Beatty

Character: Mrs. Jameson, Brandon Housekeeper

Peter Willes

Character: Lloyd Brandon

Mary Gordon

Character: Mrs. Hudson

Holmes Herbert

Character: Justice of the Court

George Regas

Character: Henchman Mateo

Mary Forbes

Character: Lady Conyngham

Frank Dawson

Character: Dawes, Moriarty's servant

William Austin

Character: Inquisitive Stranger

Anthony Kemble-Cooper

Character: Tony Conyngham

Leonard Mudie

Character: Barrows - Moriarty's Attorney (uncredited)

Robert Nobel

Character: Foreman of the Jury (uncredited)

Ivan F. Simpson

Character: Gates - Trial Prosecutor (uncredited)

Neil Fitzgerald

Character: Clerk of the Court (uncredited)

Frank Baker

Character: Tompkins (uncredited)

Denis Greene

Character: Denis Green (uncredited)

Robert Cory

Character: Tower Sentry (uncredited)

Gordon Hart

Character: Guard (uncredited)

Keith Hitchcock

Character: Constable (uncredited)

Ivo Henderson

Character: Bobby (uncredited)

Leyland Hodgson

Character: Bobby (uncredited)

Boyd Irwin

Character: Bobby (uncredited)

Charles Irwin

Character: Marine Sergeant (uncredited)

Robert R. Stephenson

Character: Cabby (uncredited)

Harry Cording

Character: Second Fake Constable (uncredited)

Eric Wilton

Character: Conyngham Butler (uncredited)

Frank Benson

Character: Cockney (uncredited)

Ted Billings

Character: Pub Customer (uncredited)

Herbert Evans

Character: Scotland Yard Man (uncredited)