Charlie Sheen

Character: Charlie B. Barkin (voice)

Dom DeLuise

Character: Itchy Itchiford (voice)

Adam Wylie

Character: David (voice)

Sheena Easton

Character: Sasha La Fleur (voice)

Ernest Borgnine

Character: Carface (voice)

George Hearn

Character: Red (voice)

Bebe Neuwirth

Character: Anabelle (voice)

Hamilton Camp

Character: Chihuahua (voice)

Steve Mackall

Character: Short Customs Dog (voice)

Dan Castellaneta

Character: Tall Customs Dog / Angel Dog #1 (voice)

Tony Jay

Character: Reginald (voice)

Jim Cummings

Character: Jingles (voice)

Wallace Shawn

Character: Labrador MC (voice)

Kevin Michael Richardson

Character: St. Bernard / Officer Andrews (voice)

Pat Corley

Character: Officer McDowell (voice)

Maurice LaMarche

Character: Lost & Found Officer (voice)