Salli Saffioti

Character: Clawdeen Wolf / Cleo de Nile (voice)

Kate Higgins

Character: Frankie Stein / Airport Announcer / Catrine DeMew (voice)

Erin Fitzgerald

Character: Abbey Bominable / Rochelle Goyle / C.A. Cupid / Spectra (voice)

Cindy Robinson

Character: Madame Ghostier / Jackson Jekyll / Holt Hyde / Operetta (voice)

Debi Derryberry

Character: Draculaura (voice)

Laura Bailey

Character: Lagoona Blue / Bloodgood / Skelita Calaveras (voice)

Stephanie Sheh

Character: Jinafire Long (voice)

Audu Paden

Character: Ghoulia Yelps / Mr. Hackington / Yeti / Sea Monster (voice)

America Young

Character: Howleen Wolf / Toralei Stripe (voice)

Ogie Banks

Character: Clawd Wolf (voice)

Evan Smith

Character: Deuce Gorgon / Garrott DuRoque / Gillington 'Gil' Webber (voice)

Cam Clarke

Character: Heath Burns / Mr. Rotter (voice)

Julie Maddalena

Character: Robecca Steam / Venus McFlytrap (voice)

Garrett Sander

Character: Ghost Cat (voice)

Jonathan Lipow

Character: Tiki People (voice)

Dustin McKenzie

Character: Clawdeen's Design Book (voice)