Glenn Close

Character: Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca")

Cameron Diaz

Character: Carol Faber (segment "Love Waits For Kathy")

Calista Flockhart

Character: Christine Taylor (segments "Goodnight Lilly, Goodnight Christine" and "This is Dr. Keener")

Kathy Baker

Character: Rose (segments "Someone For Rose" and "Fantasies about Rebecca")

Amy Brenneman

Character: Detective Kathy Faber (segment "Love Waits For Kathy")

Valeria Golino

Character: Lilly (segment "Goodnight Lilly, Goodnight Christine")

Holly Hunter

Character: Rebecca Waynon (segment "Fantasies About Rebecca")

Matt Craven

Character: Walter (segments "Fantasies About Rebecca" and "Love Waits For Kathy")

Gregory Hines

Character: Robert (segment "Fantasies About Rebecca")

Miguel Sandoval

Character: Sam (segment "Love Waits For Kathy")

Noah Fleiss

Character: Jay (segment "Someone For Rose")

Danny Woodburn

Character: Albert (segments "Someone For Rose" and "Love Waits For Kathy")

Penelope Allen

Character: Nancy (segment "Fantasies About Rebecca")

Roma Maffia

Character: Debbie (segments "Fantasies About Rebecca" and "Love Waits For Kathy")

Mika Boorem

Character: June (segments "Love Waits For Kathy" and "Goodnight Lilly, Goodnight Christine")

Irma St. Paule

Character: Elaine's Mother (segment "This is Dr. Keener")

Juanita Jennings

Character: Nurse (segment "Fantasies About Rebecca")

Laura Leigh Hughes

Character: Receptionist (segment "Fantasies About Rebecca")

Erik King

Character: Police Officer (segment "Love Waits For Kathy")

Elpidia Carrillo

Character: Carmen Alba

Yolanda Arroyo

Character: Angelica

Jacob Avnet

Character: Jay's School Friend (segment "Someone For Rose") (Uncredited)

George E. Roberts

Character: Mover (Uncredited)

Carmel Wynne Smith

Character: Bank Teller (Uncredited)