Steve Carell

Character: Gru (voice)

Jason Segel

Character: Vector (voice)

Miranda Cosgrove

Character: Margo (voice)

Dana Gaier

Character: Edith (voice)

Elsie Fisher

Character: Agnes (voice)

Russell Brand

Character: Dr. Nefario (voice)

Julie Andrews

Character: Gru's Mother (voice)

Will Arnett

Character: Mr. Perkins (voice)

Kristen Wiig

Character: Miss Hattie (voice)

Pierre Coffin

Character: Tim / Bob / Mark / Phil / Stuart (voice)

Chris Renaud

Character: Dave (voice)

Jemaine Clement

Character: Jerry (voice)

Jack McBrayer

Character: Carnival Barker / Tourist Dad (voice)

Danny McBride

Character: Fred McDade (voice)

Mindy Kaling

Character: Tourist Mom (voice)

Rob Huebel

Character: Anchorman (voice)

Ken Daurio

Character: Egyptian Guard (voice)

Ken Jeong

Character: Talk Show Host (voice)

Charles Bright

Character: Additional Voices (voice)

Katie Leigh

Character: Additional Voices (voice)

Ranjani Brow

Character: Additional Voices (voice)

Scott Menville

Character: Additional Voices (voice)

Holly Dorff

Character: Additional Voices (voice)

Edie Mirman

Character: Additional Voices (voice)

Jackie Gonneau

Character: Additional Voices (voice)

Al Rodrigo

Character: Additional Voices (voice)

Wendy Hoffmann

Character: Additional Voices (voice)

Jakob Roston

Character: Additional Voices (voice)

James Kyson

Character: Additional Voices (voice)

John Hans Tester

Character: Additional Voices (voice)

Tony Lee

Character: Additional Voices (voice)

Debi Mae West

Character: Additional Voices (voice)