Daveigh Chase

Character: Lilo (voice)

Chris Sanders

Character: Stitch / Leroy (voice)

Tia Carrere

Character: Nani (voice)

Zoe Caldwell

Character: Grand Councilwoman (voice)

Kevin McDonald

Character: Pleakley (voice)

Kevin Michael Richardson

Character: Gantu (voice)

Rob Paulsen

Character: Reuben (voice)

Jeff Bennett

Character: Hamsterviel (voice)

David Ogden Stiers

Character: Jumba (voice)

Tara Strong

Character: Angel / Belle / Houdini / Pleakley's GACC Assistant (voice)

Debra Rogers

Character: First Officer Ombit (voice)

Ving Rhames

Character: Cobra Bubbles (voice)

Liliana Mumy

Character: Mertle Edmonds (voice)

Frank Welker

Character: Sparky / Sprout / Mr. Stenchy / Kixx / Hoilo / Slugger (voice)

Nancy Cartwright

Character: Shortstuff / Phantasmo (voice)

Bobcat Goldthwait

Character: Nosy (voice)

Doug Stone

Character: Ensign Getco (voice)

Tress MacNeille

Character: Bonnie / Poxy / Gigi / Topper / Felix / Melty / Amnesio / Cannonball / GACC Van Computer (voice)

Jim Cummings

Character: Heckler (voice) (uncredited)

Jillian Henry

Character: Elena (voice)

Lili Ishida

Character: Yuki (voice)

Rocky McMurray

Character: Clyde (voice)

Kali Whitehurst

Character: Teresa (voice)