Tim Allen

Character: Eliot Arnold

Rene Russo

Character: Anna Herk

Ben Foster

Character: Matt Arnold

Jason Lee

Character: Puggy

Stanley Tucci

Character: Arthur Herk

Dennis Farina

Character: Henry Desalvo

Zooey Deschanel

Character: Jenny Herk

Janeane Garofalo

Character: Monica Romero

Sofía Vergara

Character: Nina

Tom Sizemore

Character: Snake

Johnny Knoxville

Character: Eddie

Omar Epps

Character: Seitz

Heavy D

Character: Greer

Patrick Warburton

Character: Walter Kramitz

Jack Kehler

Character: Leonard

DJ Qualls

Character: Andrew

Michael McShane

Character: Bruce

Andy Richter

Character: Jack/Ralph Pendick

Daniel London

Character: John

Lars Arentz-Hansen

Character: Leo

Cullen Douglas

Character: Captain Justin Hobart

Flip Schultz

Character: Co-Pilot Jan Vigushin

Patrick Mickler

Character: Cigar Buddy

Gerald Owens

Character: Cigar Buddy

Mitchell Carrey

Character: Cigar Buddy

Nathalie Latronico

Character: Heather Weintraub

Jon Kasdan

Character: Jack Pendick Trainee

Ian Marioles

Character: Editorial Assistant

Philip Nolen

Character: Deeber

David Koepp

Character: Annoyed Sports Radio Host (voice)

Barry Sonnenfeld

Character: Confused Sports Radio Call In (voice)

Jay Rasumny

Character: Courier #1

Ruben Gomez

Character: Courier #2

Antoni Corone

Character: William Spaulding

Siobhan Fallon Hogan

Character: Fly by Air Ticket Agent

Kava Stewartson

Character: Sour Airport Security

Gloria Laino

Character: Airport X-Ray Operator

Carmen López

Character: Airport Stern Security Woman

Mark Salem

Character: Fly By Air Baggage Handler

Renato Campilongo

Character: Gang Leader

Marc Macaulay

Character: Arch Ridley

James Martin Kelly

Character: Geo Salesman

Dave Corey

Character: Cellmate Dwight

Selma Cipes

Character: Retiree #1

Sid Raymond

Character: Retiree #2

Jody Wilson

Character: Retiree #3

Maurice Alvey

Character: Retiree #4

Mia Finnegan

Character: Aerobics Announcer (voice)

Eric Geller

Character: Aerobics Announcer (voice)

Paul Barth

Character: Airline Pilot

Martha Stewart

Character: Herself

Deborah Smith Ford

Character: Bag Lady (uncredited)

Ron Madoff

Character: Extra