Josh Hartnett

Character: Donald Morton

Radha Mitchell

Character: Isabelle Sorenson

Gary Cole

Character: Wallace

Sheila Kelley

Character: Janice

Erica Leerhsen

Character: Bronwin

John Carroll Lynch

Character: Gregory

Nate Mooney

Character: Roger

Rusty Schwimmer

Character: Gracie

Robert Wisdom

Character: Blume

Allen Evangelista

Character: Skeets

Christa Campbell

Character: Therapist

Kristopher Higgins

Character: Brain - Donald's Brother

Kelly B. Eviston

Character: Dr. Trask

Jhon Goodwin

Character: Rodney

Jeffrey Brandle

Character: Ten-year-old Kid

Hollis Higgins

Character: Homeless Man

Bil Childress

Character: Handsome Stranger

Christopher Gabble

Character: Fifteen year old Donald

Shelli Lether

Character: Donald's Mom

Mercedee Smith

Character: Young Isabella

Sharif Shawkat

Character: Young Donald

Patrick McHenry-Kroetch

Character: Mac

Norm McBride

Character: Boss

Jerry Sciarrio

Character: Flower Truck Driver

Suzanne Niles

Character: Hostess

Herb Tsuchiya

Character: Taxi Passenger #1

Mune Nakano

Character: Taxi Passenger #2

J.P. O'Shaughnessy

Character: Old Guy

Wonder Russell

Character: School Teacher

Scott Roddan

Character: Self