Nagarjuna Akkineni

Character: Nageswar Rao / Seetharamudu / Bittu

Nageshwara Rao Akkineni

Character: Chaitanya

Naga Chaitanya Akkineni

Character: Nagarjuna / Radha Mohan

Shriya Saran

Character: Rama Lakshmi / Anjali

Samantha Ruth Prabhu

Character: Krishna Veni / Priya

Brahmanandam

Character: Girish Karnad

Ali Basha

Character: Leonardo DiCaprio

Posani Krishna Murali

Character: Inspector Dharma

Jayaprakash Reddy

Character: Home Minister J.P.

Shankar Melkote

Character: Yashwanth Rayudu

Saranya Ponvannan

Character: Seetharamudu's Mother

Satya Krishnan

Character: Lecturer

Tejaswi Madivada

Character: Divya

M. S. Narayana

Character: Father Francis

Duvvasi Mohan

Character: Home Minister's Assistant

Gundu Sudarshan

Character: Marriage Broker

Saptagiri

Character: Nagarjuna's Friend

Krishnudu

Character: Doctor

Srinivasa Reddy

Character: Car Broker

Chalapathi Rao

Character: Merchant

Amitabh Bachchan

Character: Pratap (Special Appearance)

Amala Akkineni

Character: Dance Teacher (Special Appearance)

Akhil Akkineni

Character: Akhil (Special Appearance)

Neetu Chandra

Character: Air Hostess (Special Appearance)

Raashii Khanna

Character: Prema (Special Appearance)

Lavanya Tripathi

Character: Radha Mohan's Friend (Special Appearance)