Basil Rathbone

Character: Sherlock Holmes

Nigel Bruce

Character: Doctor Watson

Evelyn Ankers

Character: Kitty

Reginald Denny

Character: Sir Evan Barham

Thomas Gomez

Character: R.F. Meade

Henry Daniell

Character: Sir Anthony Lloyd

Montagu Love

Character: General Jerome Lawford

Olaf Hytten

Character: Admiral Sir John Fabian Prentiss

Leyland Hodgson

Character: Captain Roland Shore

Mary Gordon

Character: Mrs. Hudson

Hillary Brooke

Character: Jill Grandis

Harry Cording

Character: Camberwell

Herbert Evans

Character: Smithson - Barham's Butler (uncredited)

Fred Graham

Character: Meade's Henchman (uncredited)

Gavin Muir

Character: BBC Radio Announcer (voice) (uncredited)

Edgar Barrier

Character: Voice of Terror (voice) (uncredited)

Bobby Hale

Character: Bar Patron (uncredited)