John Candy

Character: Jack Gable

Mariel Hemingway

Character: Janet Dubois / Louise

Emma Samms

Character: Rachel Hedison / Laura Claybourne

Raymond Burr

Character: Carter Hedison

Dylan Baker

Character: Blake Hedison

Charles Rocket

Character: Ty Hedison

David Rasche

Character: Dr. Paul Kirkwood / Dennis

Andrea Thompson

Character: Nurse Helen Caldwell

Zach Grenier

Character: Mickey

Jerry Orbach

Character: Lou Sherwood

Renée Taylor

Character: Arlene Sherwood

Milt Oberman

Character: Fetterman

Mark Boone Junior

Character: Cable Man

Tony Steedman

Character: Edward

John Michael Bolger

Character: Len

Rita Gomez

Character: Marge

Stephanie Segal

Character: TV Reporter

Mark Zuelke

Character: Chauffeur

Dick Durock

Character: Riley

Anthony G. Schmidt

Character: Mason

Murray Rubin

Character: Manny

Peter Bromilow

Character: Auctioneer

Patrick Bristow

Character: Bellboy

Jason Ross-Azikiwe

Character: Manu

Brooke Ashley

Character: Cheerleader Donna McKenzie

Glenn Dixon

Character: Elderly Man

Paul Tuerpe

Character: Waiter

Fred Morsell

Character: Choking Man

Zack Phifer

Character: Attendant

Susan Isaacs

Character: Marie

Marvin Kaplan

Character: Typewriter Repairman

Elaine Swayneson

Character: Secretary

Jay Della

Character: Ashford Falls Cable Man

Michael Caldwell

Character: Busboy

Bill Wittman

Character: Soap Announcer

Robert M. Bouffard

Character: Office Clerk (uncredited)

Robert David Crane

Character: Bob (uncredited)

Margot Kidder

Character: Woman in Washroom (uncredited)

Tom Mankiewicz

Character: Man on Stretcher (uncredited)

Robert Wagner

Character: Jack Gates (uncredited)