Ron Fazio

Character: The Toxic Avenger (voice) / Apocalypse Inc. Executive

John Altamura

Character: The Toxic Avenger

Phoebe Legere

Character: Claire

Rick Collins

Character: Apocalypse Inc. Chairman

Rikiya Yasuoka

Character: Big Mac

Tsutomu Sekine

Character: Announcer

Mayako Katsuragi

Character: Masami

Shinoburyû

Character: Shockikuyama

Lisa Gaye

Character: Malfaire

Jessica Dublin

Character: Mrs. Junko

Jack Cooper

Character: Mr. Junko

Erika Schickel

Character: Psychiatrist

Karen King

Character: Bad Girl

Melissa Osborne

Character: Bad Girl

Helen Wheels

Character: Bad Girl

Bonnie Garvin

Character: Bad Girl

Traci Mann

Character: Apprentice Bad Girl

Raven Skye

Character: Apprentice Bad Girl

Michael Jai White

Character: Apocalypse Inc. Executive

Joe Fleishaker

Character: Apocalypse Inc. Executive

William Decker

Character: Apocalypse Inc. Executive

Dan Snow

Character: Cigarface

Andrew Wolk

Character: Pus Man

Eric Alan

Character: Homeless Couple

Felix Cortes

Character: Taxi Driver

William E. Benson

Character: Father O'Reilly

Elliot Weiss

Character: Dog Face

Arthur M. Jolly

Character: Blind Choir Singer

Charlotte Kaufman

Character: Blind Baby

Lily Hayes Kaufman

Character: Toxic Child

Lisbeth Kaufman

Character: Toxic Child

Patricia Kaufman

Character: Diaper Changer / Masami’s Voice (voice / uncredited)

Jeffrey W. Sass

Character: Good Person of Tromaville

Harry Williams Jr.

Character: Good Person of Tromaville

David Greenspan

Character: Good Person of Tromaville

Maya Shiraki

Character: Chain-Sickle Girl

Kei Nakata

Character: Sumo Wrestler

Lloyd Kaufman

Character: Sumo Wrestler / Fish Salesman (voice)

Go Nagai

Character: Tsukudani Expert

Zeeko Uchiyama

Character: Person at Odaiba Beach

Paul Borghese

Character: Lou Sipher (uncredited)

Scott Leva

Character: The Dark Rider (uncredited)