Frank Welker

Character: Freddie Jones / Scooby-Doo (voice)

Mindy Cohn

Character: Velma Dinkley (voice)

Grey DeLisle

Character: Daphne Blake (voice)

Matthew Lillard

Character: Shaggy Rogers (voice)

Robin Atkin Downes

Character: Fortius / Announcer (voice)

Troy Baker

Character: Sergey Plotnikov (voice)

Josh Keaton

Character: Steve Looker (voice)

Janet Montgomery

Character: Diane (voice)

James Patrick Stuart

Character: Jack Riggins / Igor (voice)

Domitilla D'Amico

Character: Daphne Blake (uncredited)