Jack Nicholson

Character: Melvin Udall

Helen Hunt

Character: Carol Connelly

Greg Kinnear

Character: Simon Bishop

Cuba Gooding Jr.

Character: Frank Sachs

Shirley Knight

Character: Beverly Connelly

Jesse James

Character: Spencer Connelly

Yeardley Smith

Character: Jackie Simpson

Lupe Ontiveros

Character: Nora Manning

Skeet Ulrich

Character: Vincent Lopiano

Harold Ramis

Character: Dr. Bettes

Lawrence Kasdan

Character: Dr. Green

Bibi Osterwald

Character: Neighbor Woman

Ross Bleckner

Character: Carl

Bernadette Balagtas

Character: Caterer

Jaffe Cohen

Character: Partygoer

Laurie Kilpatrick

Character: Partygoer

Alice Vaughn

Character: Partygoer

Brian Doyle-Murray

Character: Handyman

Kristi Zea

Character: Mother at Table

Annie Maginnis Tippe

Character: Daughter at Table

Patricia Childress

Character: Cafe 24 Waitress

Rebekah Johnson

Character: Cafe 24 Waitress

Missi Pyle

Character: Cafe 24 Waitress

Leslie Stefanson

Character: Cafe 24 Waitress

Tara Subkoff

Character: Cafe 24 Waitress

Shane Black

Character: Cafe 24 Manager

Peter Jacobson

Character: Man at Table

Lisa Edelstein

Character: Woman at Table

Stan Bly

Character: Cafe 24 Customer

Randall Batinkoff

Character: Carol's Date

Jamie Kennedy

Character: Street Hustler

Justin Herwick

Character: Street Hustler

Maya Rudolph

Character: Policewoman

John F. O'Donohue

Character: Detective Ray

Dr. David A. Kipper

Character: Hospital Doctor

Mary Elizabeth Still

Character: Nurse Receptionist

Chloe Brooks

Character: Child at Cafe 24

Cooper Brooks

Character: Child at Cafe 24

Sharon L. Alexander

Character: Female Passerby

Holly Denys

Character: Female Passerby

Alison Rose

Character: Psychiatric Patient

Kathryn Morris

Character: Psychiatric Patient

Wood Harris

Character: Cafe 24 Busboy

Linda Gehringer

Character: Publisher

Julie Benz

Character: Receptionist

Antonia Jones

Character: Nurse

Kaitlin Hopkins

Character: Woman in Lobby

Jimmy Workman

Character: Sean from the Bakery

Danielle Spencer

Character: Veterinarian

Todd Solondz

Character: Man on Bus

Tom McGowan

Character: Maitre'd

Danielle Brisebois

Character: Singer

Matt Malloy

Character: Men's Store Salesman

Paul Greenberg

Character: Bar Waiter

Kirk Ringberg

Character: Food Waiter

Dave Hawthorne

Character: Bartender

Dunya Djordjevic

Character: Art Dealer (uncredited)

Alex Ballar

Character: Flower Store Customer (uncredited)

Jason Thomas Campbell

Character: Valet (uncredited)

Amy Anzel

Character: Ballet Dancer (uncredited)

Eliza Harris

Character: Ballet Dancer (uncredited)

Eddie L. Fauria

Character: NYC Transit Cop (uncredited)

Frank Slaten

Character: Miffed Party Goer (uncredited)

Laura Mayes Byrnes

Character: Restaurant Patron (uncredited)

Oriana Nicole Tavoularis

Character: Restaurant Patron (uncredited)

Roger Ferreira

Character: Restaurant Patron (uncredited)

Bronwyn Cornelius

Character: Bartender (uncredited)

Maurice LaMarche

Character: Fred Bishop - Simon's Dad on Phone (voice) (uncredited)

Ava Lee Scott

Character: New Yorker