Patrick Fugit

Character: Bickford Shmeckler

Fran Kranz

Character: Ralph

Olivia Wilde

Character: Sarah Witt

John Cho

Character: Bob

Reid Scott

Character: Trent

Matthew Lillard

Character: Spaceman

Cheryl Hines

Character: Professor Adams

Thomas Lennon

Character: Campus Cop

Robert Ben Garant

Character: Campus Cop

Deon Richmond

Character: Red

Tyler Francavilla

Character: PJ

Chris Weitz

Character: Sheldon Schmeckler (voice)

J.D. Walsh

Character: Fred

Gary Lundy

Character: Mellow Guy

Genevieve Padalecki

Character: Toga Hussy

Wes Ramsey

Character: Rob

Greg Pitts

Character: Doug the Dungeon Master

Simon Helberg

Character: Al

Mageina Tovah

Character: Sam

J.B. Ghuman Jr.

Character: Bill

Natalie Garza

Character: Alpha Zeta Sister

Nicole Garza

Character: Alpha Zeta Sister

Tiffany Dupont

Character: Alpha Zeta Sister

Clark Gregg

Character: Publisher