Boris Karloff

Character: Dr. Fu Manchu

Lewis Stone

Character: Nyland Smith

Karen Morley

Character: Sheila Barton

Charles Starrett

Character: Terence Granville

Myrna Loy

Character: Fah Lo See

Jean Hersholt

Character: Von Berg

Lawrence Grant

Character: Sir Lionel Barton

David Torrence

Character: McLeod

C. Montague Shaw

Character: Curator Dr. Fairgyle - British Museum Official (uncredited)

Steve Clemente

Character: Knife Thrower (uncredited)

Allen Jung

Character: Coolie (uncredited)

Chris-Pin Martin

Character: Potentate (uncredited)

Edward Peil Sr.

Character: Coolie Spy (uncredited)

Willie Fung

Character: Ship's Steward (uncredited)

E. Alyn Warren

Character: Goy Lo Sung - Fu Manchu Messenger (uncredited)

Olive Young

Character: Cantina singer (uncredited)

Everett Brown

Character: Slave (uncredited)

Clinton Rosemond

Character: Slave (uncredited)