Woody Harrelson

Character: Dr. Michael Reynolds

Jon Seda

Character: Brandon 'Blue' Monroe

Anne Bancroft

Character: Dr. Renata Baumbauer

Alexandra Tydings

Character: Victoria Reynolds

Matt Mulhern

Character: Dr. Chip Byrnes

Talisa Soto

Character: Navajo Woman

Richard Bauer

Character: Dr. Bradford

Victor Aaron

Character: Webster Skyhorse

Lawrence Pressman

Character: Agent in Charge Collier

Michael O'Neill

Character: Agent Moreland

Harry Carey, Jr.

Character: Cashier

Carmen Dell'Orefice

Character: Arabella Reynolds

Brooke Ashley

Character: Calantha Reynolds

Andrea Roth

Character: Head Nurse

Bob Minor

Character: Deputy Lynch

Sal Landi

Character: Deputy #2

Harper Roisman

Character: Mr. Vogel

Kelly Perine

Character: Fellow in Oncology

Andy Berman

Character: Fellow in Oncology

Kirsten Getchell

Character: Sally Byrnes

Emil Alexander

Character: Waiter

John Christian Graas

Character: Young Michael Reynolds

Christopher Masterson

Character: Jimmy Reynolds

Antwon Tanner

Character: Smokes

Pam Morton

Character: Self

Linda M. Duenas

Character: Waitress

Tony Epper

Character: Hay Hauler

Mickey Jones

Character: Fuzzy, Biker #1

Gregory Scott Cummins

Character: Biker #2

Douglas B. Hall

Character: State Trooper

Dan B. Pastre

Character: State Trooper

Elaine Kagan

Character: Woman at Gas Station

Robert 'Bobby Z' Zajonc

Character: FBI Helicopter Pilot

Jeri Arredondo

Character: Hospital Pharmacist

Brian Bossetta

Character: Hospital Security Guard

Cynthia Allison

Character: CNN Reporter

Carolyn Tomlin

Character: Hospital Spokesperson

Brian K. Francis

Character: Navajo Boy

Alan Keller

Character: Older Highway Patrol Officer

Brett Harrelson

Character: Younger Highway Patrol Officer

Zoe Trilling

Character: Mini-Mart Cashier

Betty Carvalho

Character: Rosa

Matthew Abe

Character: Surgeon

Eugene Boggs

Character: Surgeon

Philip Zachary

Character: Disc Jockey

David Green

Character: First Inmate

Askia Won-Ling Jacob

Character: UCLA Student

Robert Downey Sr.

Character: Telephone Voices