Robert De Niro

Character: Jack Byrnes

Ben Stiller

Character: Greg Focker

Owen Wilson

Character: Kevin Rawley

Dustin Hoffman

Character: Bernie Focker

Barbra Streisand

Character: Rozalin Focker

Blythe Danner

Character: Dina Byrnes

Teri Polo

Character: Pam Byrnes-Focker

Jessica Alba

Character: Andi Garcia

Laura Dern

Character: Prudence

Kevin Hart

Character: Nurse Louis

Daisy Tahan

Character: Samantha Focker

Colin Baiocchi

Character: Henry Focker

Tom McCarthy

Character: Dr. Bob

Harvey Keitel

Character: Randy Weir

Yul Vazquez

Character: Junior

Jack Axelrod

Character: Chappy

Clent Bowers

Character: Mr. Androvsky

Olga Fonda

Character: Svetlana

Laksh Singh

Character: Dr. Patel

Trula M. Marcus

Character: Stage Producer

Jake Keiffer

Character: Rufus

Rob Huebel

Character: Sleazy Doctor

John DiMaggio

Character: EMT

Jordan Peele

Character: EMT

Kelli Kirkland

Character: EMT

Deepak Chopra

Character: Deepak Chopra

Robbie Tucker

Character: EHS Tough Kid

Nick Kroll

Character: Young Doctor

Sergio Calderón

Character: Gustavo

Aaron Zachary Philips

Character: Confused Child

David Pressman

Character: Doctor

Hugh Dane

Character: Doctor

Amy Stiller

Character: Kristen

Richard Cotovsky

Character: Newspaper Vendor

Trinity Warren

Character: Climbing Kid

Samuel Schultz

Character: Climbing Kid

Cade Rogers

Character: Climbing Kid / Bounce House Kid

Ava Rose Williams

Character: Climbing Kid

Frankie Torres

Character: Climbing Kid

Kyla Warren

Character: Party Kid

Erin Haisan

Character: Party Kid

Ryder Bucaro

Character: Party Kid

Callder Griffith

Character: Party Kid

Lei'lah Star

Character: Party Kid

David Williams

Character: Party Kid

Randy Chuang

Character: Monk

Joe Thamawat

Character: Monk

Harry Bali

Character: Sadu

Paul Herman

Character: Caricature Artist

Leslie Garavito

Character: Fire Pit Child

Cort Rogers

Character: Bounce House Kid

Troy Lindsay Brown

Character: Bounce House Kid

Erika Jensen

Character: Party Parent

Robert Miano

Character: Party Parent

Kat Kramer

Character: Party Parent

Roy Jones Jr.

Character: Party Parent

Derek Ressallat

Character: Party Parent

Vladimir Kubr

Character: Ballpit Kid

Semere-Ab Etmet Yohannes

Character: Fire Walker

Nicole Pano

Character: Art Teacher

Michael Naughton

Character: Anatomy Professor

Celina Zambón

Character: Carmencita

Shih Chou

Character: Party Monk

Stan Egi

Character: Man on Subway

Juan Antonio Bolivar

Character: Flamenco Dancer

Michelle Castillo

Character: Flamenco Dancer

Theo Crisell

Character: Flamenco Dancer

Neisha Folkes-LeMelle

Character: Flamenco Dancer

Jillana Laufer

Character: Flamenco Dancer

Molly Rogers

Character: Flamenco Dancer

Gary Sievers

Character: Spanish Square Patron (uncredited)

Arnold Chon

Character: Monk (uncredited)