William Powell

Character: Clarence Day Sr.

Irene Dunne

Character: Vinnie Day

Elizabeth Taylor

Character: Mary Skinner

Edmund Gwenn

Character: Rev. Dr. Lloyd

Zasu Pitts

Character: Cousin Cora Cartwright

Jimmy Lydon

Character: Clarence Day Jr.

Emma Dunn

Character: Margaret

Moroni Olsen

Character: Dr. Humphries

Elisabeth Risdon

Character: Mrs. Whitehead

Derek Scott

Character: Harlan Day

Johnny Calkins

Character: Whitney Benjamin Day

Martin Milner

Character: John Day

Heather Wilde

Character: Annie

Monte Blue

Character: The Policeman

Mary Field

Character: Nora

Clara Blandick

Character: Miss Wiggins

Arlene Dahl

Character: Girl at Delmonico's (uncredited)

Creighton Hale

Character: Mr. Wickersham the Father of Twin Boys (uncredited)

Dick Gordon

Character: Waiter at Delmonico's (uncredited)