David Arquette

Character: Dewey Riley

Neve Campbell

Character: Sidney Prescott

Courteney Cox

Character: Gale Weathers

Patrick Dempsey

Character: Mark Kincaid

Scott Foley

Character: Roman Bridger

Lance Henriksen

Character: John Milton

Matt Keeslar

Character: Tom Prinze

Jenny McCarthy

Character: Sarah Darling

Emily Mortimer

Character: Angelina Tyler

Parker Posey

Character: Jennifer Jolie

Deon Richmond

Character: Tyson Fox

Kelly Rutherford

Character: Christine Hamilton

Liev Schreiber

Character: Cotton Weary

Patrick Warburton

Character: Steven Stone

Jamie Kennedy

Character: Randy Meeks

Julie Janney

Character: Moderator

Roger L. Jackson

Character: 'The Voice' (voice)

Richmond Arquette

Character: Student

Nancy O'Dell

Character: Female Reporter

Ken Taylor

Character: Male Reporter

Lynn McRee

Character: Maureen Prescott

Roger Corman

Character: Studio Executive

Josh Pais

Character: Wallace

John Embry

Character: Stage Security Guard

Lawrence Hecht

Character: Neil Prescott

Lisa Beach

Character: Studio Tour Guide

Kevin Smith

Character: Silent Bob

Jason Mewes

Character: Jay

Erik Erath

Character: Stan

Daniel K. Arredondo

Character: Office Security Guard

Lisa Gordon

Character: Waitress

Heather Matarazzo

Character: Martha Meeks

Carrie Fisher

Character: Bianca Burnette

C.W. Morgan

Character: Hank Loomis

Beth Toussaint

Character: Female Caller (voice)

Wes Craven

Character: Man with Video Camera on Studio Tour (uncredited)