Rose Byrne

Character: Rebecca Skloot

Renée Elise Goldsberry

Character: Henrietta Lacks

Oprah Winfrey

Character: Deborah Lacks

Ninja N. Devoe

Character: Country Girl Mae

Lisa Arrindell

Character: Aunt Ethel

Earl Poitier

Character: Cousin Josh

L. Warren Young

Character: Day Lacks

Patrick Walker

Character: Cousin Fred

Jane Rumbaua

Character: Mrs. Hsu

Sylvia Grace Crim

Character: Mary Kubicek

Tian Richards

Character: Lawrence (16 yrs.)

Kate Bond

Character: Young Woman

Jazzy Ellis

Character: Young Gladys

Jock McKissic

Character: Carl the Mechanic

Kyanna Simone Simpson

Character: Deborah (15-24YRS)

Tinashe Kajese

Character: Sadie

Kayla Anderson

Character: Johns Hopkins Student

Karen Wheeling Reynolds

Character: Mrs. Gey

Todd Lee

Character: Doctor

Jordan Eli Arellano

Character: Young Sonny Lacks

Mary Shaw

Character: Woman at Pump

Tatom Pender

Character: Johns Hopkins Nurse

Christopher Robert Escobar

Character: Chris the Intern

Clint Edwards

Character: Scientist

De'Marco Arrington

Character: Young Joe

Jaylon Gordon

Character: Alfred

Tashaun Stanfill-Perry

Character: Henrietta Lacks Neighbor

Matthew Bernard

Character: Johns Hopkins Student

Sage Mayer

Character: Young Boy

Elizabeth Hackler

Character: Rebecca's Co-worker

David Shae

Character: Reporter

Jaedon Godley

Character: Davon Lacks

Tyvonna Jones

Character: Elsie Lacks

Raphael Dante' Carr Jr.

Character: Young Sonny

Miguel Angel Marrero

Character: Scientist

Courtney B. Vance

Character: Sir Lord Keenan Coefield

Reed Birney

Character: Dr. George Gey

Alpha Trivette

Character: First Administrator

Terrence V. Walker

Character: Church Patron

Sean Freeland

Character: Charlie

Reg E. Cathey

Character: Zakariyyah

Gabriel Ebert

Character: Christoph Lengauer