Steve Carell

Character: Gru (voice)

Pierre Coffin

Character: Kevin / Stuart / Bob / Minions (voice)

Alan Arkin

Character: Wild Knuckles (voice)

Taraji P. Henson

Character: Belle Bottom (voice)

Julie Andrews

Character: Gru's Mom (voice)

Jean-Claude Van Damme

Character: Jean Clawed (voice)

Lucy Lawless

Character: Nun-Chuck (voice)

Michelle Yeoh

Character: Master Chow (voice)

Dolph Lundgren

Character: Svengeance (voice)

Danny Trejo

Character: Stronghold (voice)

Russell Brand

Character: Dr. Nefario (voice)

Jimmy O. Yang

Character: Henchman 1 (voice)

Kevin Michael Richardson

Character: Henchman 2 (voice)

John DiMaggio

Character: Henchman 3 (voice)

RZA

Character: Biker (voice)

Michael Beattie

Character: VNC Announcer / Guru Rick (voice)

Will Arnett

Character: Mr. Perkins (voice)

Steve Coogan

Character: Silas Ramsbottom (voice)

Colette Whitaker

Character: Gru's Teacher (voice)

Raymond S. Persi

Character: Birthday Kid (voice)

Kyle Balda

Character: Additional Voices (voice)

Bob Bergen

Character: Additional Voices (voice)

Beau Billingslea

Character: Additional Voices (voice)

Cathy Cavadini

Character: Additional Voices (voice)

David Chen

Character: Additional Voices (voice)

Will Collyer

Character: Additional Voices (voice)

Meilee Condron

Character: Additional Voices (voice)

Antonio Raul Garcia

Character: Additional Voices (voice)

Debi Derryberry

Character: Additional Voices (voice)

Scarlett Estevez

Character: Additional Voices (voice)

Kellen Goff

Character: Additional Voices (voice)

Jake Green

Character: Additional Voices (voice)

Isa Hall

Character: Additional Voices (voice)

Ramone Hamilton

Character: Additional Voices (voice)

Aaron Hendry

Character: Additional Voices (voice)

Barbara Harris

Character: Additional Voices (voice)

JP Karliak

Character: Additional Voices (voice)

Evan Kishiyama

Character: Additional Voices (voice)

Sam Lavagnino

Character: Additional Voices (voice)

Dawnn Lewis

Character: Additional Voices (voice)

Amari McCoy

Character: Additional Voices (voice)

Levi Nunez

Character: Additional Voices (voice)

Benjamin Plessala

Character: Additional Voices (voice)

Alex Puccinelli

Character: Additional Voices (voice)

David J. Randolph

Character: Additional Voices (voice)

Carla Rempp

Character: Additional Voices (voice)

Nhev Scharrel

Character: Additional Voices (voice)

James Sie

Character: Additional Voices (voice)

Mindy Sterling

Character: Additional Voices (voice)

Fred Tatasciore

Character: Additional Voices (voice)

Regina Taufen

Character: Additional Voices (voice)

Nisa Ward

Character: Additional Voices (voice)

Debra Wilson

Character: Additional Voices (voice)

Nora Wyman

Character: Additional Voices (voice)

Gad Elmaleh

Character: (voice) (uncredited)

Claudia Tagbo

Character: (voice) (uncredited)

Gérard Darmon

Character: (voice) (uncredited)

Jonathan Cohen

Character: (voice) (uncredited)