Tim Robbins

Character: Nathan Bronfman

Patricia Arquette

Character: Lila Jute

Rhys Ifans

Character: Puff

Miranda Otto

Character: Gabrielle

Mary Kay Place

Character: Nathan's Mother

Robert Forster

Character: Nathan's Father

Peter Dinklage

Character: Frank

Rosie Perez

Character: Louise

Hilary Duff

Character: Young Lila Jute

Miguel Sandoval

Character: Wendall the Therapist

Toby Huss

Character: Puff's Father

Ken Magee

Character: Police Detective

Sy Richardson

Character: Police Detective

David Warshofsky

Character: Police Detective

Stanley DeSantis

Character: Doctor

Bobby Harwell

Character: Congressman

Daryl Anderson

Character: Congressman

Bobby Pyle

Character: Young Puff

Chase MacKenzie Bebak

Character: Young Nathan

Anthony Winsick

Character: Wayne Bronfman

Mary Portser

Character: Bistro Waitress

Laura Grady

Character: Aversion Therapy Model

Angela Little

Character: Chester's Waitress

Deborah Ferrari

Character: Stripper

Jeremy Kramer

Character: Lecture Host

Nancy Lenehan

Character: Puff's Mother

Juan Canopii

Character: Reporter (uncredited)