James D'Arcy

Character: Sherlock Holmes

Roger Morlidge

Character: Dr. Watson

Vincent D'Onofrio

Character: Moriarty

Gabrielle Anwar

Character: Rebecca Doyle

Richard E. Grant

Character: Mycroft

Nicholas Gecks

Character: Inspector Lestrade

Struan Rodger

Character: Ben Harrington

Peter-Hugo Daly

Character: Henry Coot

Mihai Bisericanu

Character: Sgt. Cox

Sandu Mihai Gruia

Character: Dr. Cruickshank

Constantin Bărbulescu

Character: Captor #1

Doru Dumitrescu

Character: Captor #2

Natalie Ester

Character: Pretty Young Hopeful

Ioana Abur

Character: Victoria

Fritha Goodey

Character: Anna

Valentin Popescu

Character: Killer

Anca Androne

Character: Nurse