T-Pain

Character: Freaknik (voice)

Joey Galaxy

Character: Virgil (voice)

Cee Lo Green

Character: Lite Skinn'd (voice)

Rick Ross

Character: Big Uzi (voice)

DJ Pooh

Character: Doela Man (voice)

Lil Jon

Character: Foreboding Old Dude (voice)

Big Boi

Character: Preacher (voice)

DJ Drama

Character: Mr. Thanksgiving (voice)

Snoop Dogg

Character: Gang Member (voice)

Kelis

Character: (voice)

Mack Maine

Character: (voice)

Sophia Fresh

Character: Leacosia / Toprameneesha / Obamaniqua / Suzie (voice)

Lil Wayne

Character: Trap Jesus (voice)

Charlie Murphy

Character: (voice)

Bill Hader

Character: Tad (voice)

Andy Samberg

Character: Chad (voice)

George Clinton

Character: (voice)

Bootsy Collins

Character: (voice)

Kel Mitchell

Character: Fruit Bowl Boys Leader (voice)

Liz Benoit

Character: Oprah Winfrey (voice)

Gene Anderson

Character: (voice)

Reginald Boyland

Character: (voice)

Christopher Reid

Character: (voice)

Christopher Martin

Character: (voice)

Affion Crockett

Character: (voice)

Corey Burton

Character: (voice)

Carl Jones

Character: Virgil's Boss (voice)

Heather Lawless

Character: (voice)