George Clooney

Character: Jimmy 'Dodge' Connelly

Renée Zellweger

Character: Lexie Littleton

John Krasinski

Character: Carter Rutherford

Wayne Duvall

Character: Coach Frank Ferguson

Stephen Root

Character: Suds

Jonathan Pryce

Character: CC Frazier

Jack Thompson

Character: Harvey

Max Casella

Character: Mack Steiner

Matt Bushell

Character: Curly

Nick Paonessa

Character: Zoom

Malcolm Goodwin

Character: Bakes

Robert Baker

Character: Stump

Tim Griffin

Character: Ralph

Keith Loneker

Character: Big Gus

David de Vries

Character: Princeton Reporter

Rick Forrester

Character: Princeton Reporter

Tommy Hinkley

Character: Hardleg

Lance Barber

Character: Toledo Referee

Nicholas Bourdages

Character: Bug

Jason Drago

Character: Toledo Player

Bill Roberson

Character: Mr. Dunn

Hi Bedford-Roberson

Character: Mrs. Dunn

Mark Teich

Character: Joe

Christian Stolte

Character: Pete

Windy Wenderlich

Character: Conductor

Marian Seldes

Character: Clerk

Thomas Francis Murphy

Character: Cook

JD Cullum

Character: Leonard

Dave Hager

Character: Duluth Reporter

Danny Vinson

Character: Duluth Reporter

Mike O'Malley

Character: Mickey

Dylan Kussman

Character: Soldier Frank

Ryan Shively

Character: Corporal Jack

Kyle Nudo

Character: German Soldier

Heather Goldenhersh

Character: Belinda / Flapper

Grant Heslov

Character: Saul Keller

Bobby Jordan

Character: Football Player (uncredited)