Dwayne Johnson

Character: Dr. Smolder Bravestone

Kevin Hart

Character: Franklin 'Mouse' Finbar

Jack Black

Character: Professor Sheldon 'Shelly' Oberon

Karen Gillan

Character: Ruby Roundhouse

Awkwafina

Character: Ming

Nick Jonas

Character: Jefferson 'Seaplane' McDonough

Alex Wolff

Character: Spencer Gilpin

Morgan Turner

Character: Martha Kaply

Madison Iseman

Character: Bethany

Ser'Darius Blain

Character: Anthony 'Fridge' Johnson

Danny DeVito

Character: Eddie

Danny Glover

Character: Milo

Rhys Darby

Character: Nigel Billingsley

Colin Hanks

Character: Alex

Rory McCann

Character: Jurgen the Brutal

Marin Hinkle

Character: Spencer's Mom

Vince Pisani

Character: Pharmacy Manager

Dorothy Steel

Character: Village Elder

Jennifer Patino

Character: Bravestone's Mother

Madison Johnson

Character: Little Bethany Vreeke

Dania Ramirez

Character: Lady in Red

Derek Russo

Character: Key Master

Nick Gomez

Character: Oasis Drunk

Massi Furlan

Character: Switchblade

Javier Villamil

Character: Switchblade's Sidekick

Anthony Neves

Character: Jurgen's Patrolman

Morgan Brown

Character: Fortress Guard

Deobia Oparei

Character: Elevator Guard

Leslie Simms

Character: Cake Lady

John Ross Bowie

Character: Cavendish

Lucy DeVito

Character: Maiden

Bebe Neuwirth

Character: Nora

Lamorne Morris

Character: Heater Repair Guy

Darin Ferraro

Character: The Gun Seller (uncredited)

Sal Longobardo

Character: Tony (uncredited)

Michael Beasley

Character: Coach Davis (uncredited)

Charles Green

Character: Bartender (uncredited)

James William Ballard

Character: Bad Guy in Fortress (uncredited)

Kodai Yamaguchi

Character: Jumanjian Villager (uncredited)

Ashley Scott

Character: Ashley (uncredited)

Melissa Kennemore

Character: Marauder 1 / Jergens Inner Circle (uncredited)

Vanessa Cater

Character: Red Headed Marauder (uncredited)

John David Bulla

Character: Groovy Face Tattoo Biker (uncredited)

Ryan Cheeseman

Character: Marauder (uncredited)

Cruz Abelita

Character: Messenger Boy (uncredited)

Sheril Rodgers

Character: New York City Pedestrain (uncredited)

Bruno Rose

Character: NY Dorm Guy (uncredited)