Andy Samberg

Character: Nyles

Cristin Milioti

Character: Sarah

J.K. Simmons

Character: Roy

Peter Gallagher

Character: Howard

Meredith Hagner

Character: Misty

Camila Mendes

Character: Tala

Tyler Hoechlin

Character: Abe

Chris Pang

Character: Trevor

Jacqueline Obradors

Character: Pia

June Squibb

Character: Nana Schlieffen

Tongayi Chirisa

Character: Jerry

Dale Dickey

Character: Darla

Conner O'Malley

Character: Randy

Jena Friedman

Character: Daisy the Bartender

Brian Duffy

Character: Spuds

Martin Kildare

Character: Ted the Bartender

Lilli Birdsell

Character: Jamie

Ryan Sturtz

Character: Cop

Clifford V. Johnson

Character: Professor

Calki Garcia

Character: DJ Nice Height

Michelle Johnston

Character: Nosy Neighbor

Isla Sellers

Character: Roy's Daughter

Matt Smith

Character: Out of Town Dad

Rebecca Smith

Character: Out of Town Mom

Jake Smith

Character: Out of Town Older Son

Noah Smith

Character: Out of Town Younger Son

Rocky Bonifield

Character: Wedding Guest (uncredited)

Erin Flannery

Character: Wedding Guest (uncredited)

David Hutchison

Character: Biker (uncredited)

Mark Kubr

Character: Biker (uncredited)

David Philip Reed

Character: Truck Driver (uncredited)