Bette Midler

Character: Winifred Sanderson

Sarah Jessica Parker

Character: Sarah Sanderson

Kathy Najimy

Character: Mary Sanderson

Whitney Peak

Character: Becca

Belissa Escobedo

Character: Izzy

Lilia Buckingham

Character: Cassie

Froy Gutierrez

Character: Mike

Sam Richardson

Character: Gilbert

Doug Jones

Character: Billy Butcherson

Tony Hale

Character: Mayor / Reverend Traske

Hannah Waddingham

Character: The Witch Mother

Taylor Henderson

Character: Young Winifred

Nina Kitchen

Character: Young Mary

Juju Journey Brener

Character: Young Sarah

Thomas Fitzgerald

Character: John Pritchett

Brett Cramp

Character: Mr. Pritchett

Kim Niemi

Character: Townsperson

Alison Weller

Character: Townsperson

Holly Cinnamon

Character: Townsperson

Patrick French

Character: Townsperson

Charlotte Peed

Character: Mrs. Smith

Ed Peed

Character: Mr. Smith

Austin J. Ryan

Character: Young Billy Butcherson

Michael Tow

Character: Mr. Wilke

Brina

Character: School Secretary

Brian Wiles

Character: Rob

Owen Earls

Character: Liam

Skyla Sousa

Character: Teen Winifred

Aiden Torres

Character: Teen Mary

Emma Kaufman

Character: Teen Sarah

Chhoyang Cheshatsang

Character: Thom

Jaylin Pryor

Character: Teen Gilbert

Marissa Carpio

Character: Food Stall Woman

Naheem Garcia

Character: Fred

Dan Finnerty

Character: Lucas

Ginger Minj

Character: Drag Queen Winifred

Kornbread Jeté

Character: Drag Queen Mary

Kahmora Hall

Character: Drag Queen Sarah

Ryan Rosenthal

Character: Glenn

Juvan Elisma

Character: Alex

Jen D'Angelo

Character: Liam's Mom

Mark Fichera

Character: Scary Scarecrow

Jordan von Netzer

Character: Roman Soldier

Mark Hawker

Character: Puppeteer

Shane Dzicek

Character: Puppeteer

CJ Walsh

Character: Puppeteer

David Torres Jr.

Character: Teacher (uncredited)