Katherine Heigl

Character: Jane Nichols

James Marsden

Character: Kevin Doyle

Malin Åkerman

Character: Tess Nichols

Judy Greer

Character: Casey

Edward Burns

Character: George

Melora Hardin

Character: Maureen

Brian Kerwin

Character: Hal Nichols

Maulik Pancholy

Character: Trent

David Castro

Character: Pedro

Krysten Ritter

Character: Gina the Goth

Michael Paul

Character: Taxi Fahrer Khaleel

Jennifer Lim

Character: Bridal Salesgirl

Danielle Skraastad

Character: Bride Suzanne

Yetta Gottesman

Character: Hip Bridesmaid

Erin Fogel

Character: Shari Rabinowitz

Bern Cohen

Character: Rabbi

Brigitte Bourdeau

Character: Salesgirl Olga

Peyton List

Character: Young Jane

Charli Barcena

Character: Young Tess

Jane Pfitsch

Character: Cousin Lisa

Laksh Singh

Character: Hindu Priest

Lyralen Kaye

Character: Yoga Instructor

Ronald Guttman

Character: Antoine

Ron Simons

Character: Boathouse Chef

Robert Clohessy

Character: Dive Bartender

Michael Mosley

Character: Bar Dude

Alyssa Bresnahan

Character: Diner Waitress

Ellen H. Schwartz

Character: Diner Waitress

Jennifer Bassey

Character: Jane's Aunt

Alexa Havins

Character: Boat Bride

Richard O'Rourke

Character: Jane's Minister

Kathryn Weisbeck

Character: Tara Bride (uncredited)