Jeremy Brett

Character: Sherlock Holmes

Edward Hardwicke

Character: Dr. John Watson

Raymond Adamson

Character: Sir Charles Baskerville

Alastair Duncan

Character: Dr. Mortimer

Ronald Pickup

Character: Barrymore

Rosemary McHale

Character: Mrs. Barrymore

Kristoffer Tabori

Character: Sir Henry Baskerville

James Faulkner

Character: Stapleton

Edward Romfourt

Character: Purser

Philipp Dettmer

Character: Pageboy

Stephen Tomlin

Character: Perkins

Fiona Gillies

Character: Beryl Stapleton

Bernard Horsfall

Character: Frankland

Don McKillop

Character: Vicar of Grimpen

William Ilkley

Character: Selden

Myrtle Devenish

Character: Postmistress

Elizabeth Spender

Character: Laura Lyons

Donald Bisset

Character: Manservant (uncredited)