George Clooney

Character: Seth Gecko

Quentin Tarantino

Character: Richard Gecko

Harvey Keitel

Character: Jacob Fuller

Juliette Lewis

Character: Kate Fuller

Ernest Liu

Character: Scott Fuller

Salma Hayek Pinault

Character: Santanico Pandemonium

Cheech Marin

Character: Border Guard / Chet Pussy / Carlos

Danny Trejo

Character: Razor Charlie

Tom Savini

Character: Sex Machine

Fred Williamson

Character: Frost

Michael Parks

Character: Texas Ranger Earl McGraw

Brenda Hillhouse

Character: Hostage Gloria

John Saxon

Character: FBI Agent Stanley Chase

Marc Lawrence

Character: Old Timer

Kelly Preston

Character: Newscaster Kelly Houge

John Hawkes

Character: Pete Bottoms

Tito Larriva

Character: Titty Twister Guitarist & Vocalist

Peter Atanasoff

Character: Titty Twister Saxophonist

Johnny Vatos Hernandez

Character: Titty Twister Drummer

Aimee Graham

Character: Blonde Hostage

Heidi McNeal

Character: Red-headed Hostage

Ernest M. Garcia

Character: Big Emilio

Greg Nicotero

Character: Sex Machine's Buddy

Cristos

Character: Danny

Mike Moroff

Character: Manny

Michelle Berube

Character: Bar Dancer

Rosalia Hayakawa

Character: Bar Dancer

Neena Bidasha

Character: Bar Dancer

Janine Jordae

Character: Bar Dancer

Veena Bidasha

Character: Bar Dancer

Jacque Lawson

Character: Bar Dancer

Ungela Brockman

Character: Bar Dancer

Tiffany Granath

Character: Bar Dancer

Madison Clark

Character: Bar Dancer

Janie Liszewski

Character: Bar Dancer

María Díaz

Character: Bar Dancer

Tia Texada

Character: Bar Dancer

Michael McKay

Character: Monster

Jake McKinnon

Character: Monster

Walter Phelan

Character: Monster

Wayne Toth

Character: Monster

Cecilia Montiel

Character: Herself

Annette Harper

Character: Bar Dancer

Lawrence Bender

Character: Man in Diner (Uncredited)

Robert Rodriguez

Character: Band Member (uncredited)