Steve Coogan

Character: Tristram Shandy / Walter Shandy / Steve Coogan

Rob Brydon

Character: Toby Shandy / Rob Brydon

Keeley Hawes

Character: Elizabeth Shandy / Keeley Hawes

Shirley Henderson

Character: Susannah / Shirley Henderson

Raymond Waring

Character: Trim

Conal Murphy

Character: Six-Year-Old Tristam

Joe Williams

Character: Nine-Year-Old Tristam

Paul Kynman

Character: Obadiah

Mark Tandy

Character: London Doctor

Dylan Moran

Character: Dr. Slop

Jack Shepherd

Character: Surgeon

David Walliams

Character: Parson

Jeremy Northam

Character: Mark

Benedict Wong

Character: Ed

Naomie Harris

Character: Jennie

Claire Keelan

Character: Make-Up Assistant

Kelly Macdonald

Character: Jenny

Mark Hadfield

Character: Leo

Elizabeth Berrington

Character: Debbie

Mark Williams

Character: Ingoldsby

Jenny Ogilvie

Character: Sandy

Tony Wilson

Character: Tony Wilson

Justine Mitchell

Character: Tony's Director

Kieran O'Brien

Character: Gary

Roger Allam

Character: Adrian

Ashley Jensen

Character: Lindsey

James Fleet

Character: Simon

Ian Hart

Character: Joe

Ronni Ancona

Character: Anita

Greg Wise

Character: Greg

Paul Rider

Character: Prop Guy

Stephen Fry

Character: Patrick Curator / Parson Yorick

Sara Stewart

Character: Joanna

Gillian Anderson

Character: Widow Wadman / Gillian Anderson

Stephen Rodrick

Character: New York Times Reporter

Rosie Cavaliero

Character: Rachel

Damon Caliendo

Character: Fire Dancer

Andy Callaghan

Character: Playing Film Crew

Richard Tree

Character: Redcoat Officer

Mary Healey

Character: Midwife

Stuart Wilson

Character: Sound Mixer