Rosemarie DeWitt

Character: Cindy Lamson

Ron Livingston

Character: Jim Lamson

Mary-Louise Parker

Character: Roxy

Elaine May

Character: Ruth Lipsman Berg

Sandra Oh

Character: Grace Park

Moses Ingram

Character: Audre Robinson

Noma Dumezweni

Character: Dionne Davis

Raúl Castillo

Character: Nurse Joey

Alison Pill

Character: Bridget Salt

John Gallagher Jr.

Character: Dale Salt

Daphne Rubin-Vega

Character: Lupe Ramirez

Joshua Leonard

Character: Doug Salt

Jin Ha

Character: Elliot Park

Judith Light

Character: Shirlee Salt

Ato Blankson-Wood

Character: Russell Davis

Cory Michael Smith

Character: Jeremy Salt

Rhenzy Feliz

Character: Jose Sera

Camila Perez

Character: Frieda Ramirez

K. Todd Freeman

Character: Leon Robinson

Danny Burstein

Character: Dr. Daniel Berg

Joel de la Fuente

Character: John Park

Raza Jaffrey

Character: Dr. Sanjay Patel

Brittany Bradford

Character: Imani Hart

David Zaldivar

Character: Mateo Ramirez

Willa Cuthrell-Tuttleman

Character: Amy

Tim Guinee

Character: Phil H.

Jorge Charbonier

Character: Grandpa Alfredo

Bill Timoney

Character: News Reporter (voice)

Gamze Ceylan

Character: Jackie

Chris Hotlkamp

Character: John

Jerry Smith

Character: Tony

Maddie Corman

Character: Joey

Dionne Ford

Character: Louise

Elizabeth Cuthrell

Character: Shiva Guest

John Clement

Character: Shiva Guest

Dianne Dreyer

Character: Emma

Kirsten Schatz

Character: 12 Step Member

David Urrutia

Character: Shiva Guest

Emerson Witty

Character: Ben Lamson (voice)

Kyle Eaton

Character: Thomas

John Grindley

Character: Stewart

Maceo Bishop

Character: 12 Step Member

Evan Andres Fernandez

Character: Frieda's Little Brother (voice)

Ruth Moore

Character: Video Game (voice)

Rivka Rivera

Character: Maya

Henry Rivera

Character: Henry

Susan Batten

Character: Holly

Bevan Thomas

Character: Katie T.

Marcin Czarnik

Character: 12 Step Member

Willy Hedges

Character: 12 Step Member

Sadie Hedges

Character: 12 Step Member

Russ Jolly

Character: 12 Step Member

Max Ethan Miller

Character: 12 Step Member

Deb Dougal

Character: Yoga Class Participant

Sarah Oliveras

Character: Yoga Class Participant

Natasha Perez

Character: Yoga Class Participant

Rashad Pridgen

Character: Yoga Class Participant

Sahi Van-Tull

Character: Yoga Class Participant

Cornelia Do

Character: Shiva Guest

Karen Meltzer

Character: Shiva Guest

Laurie Meltzer

Character: Shiva Guest

Erik Nilsson

Character: Shiva Guest

Julie Nilsson

Character: Shiva Guest

Kip Rivers

Character: Shiva Guest

Kathleen Rivers

Character: Shiva Guest