Benicio del Toro

Character: Ernesto Che Guevara

Carlos Bardem

Character: Moisés Guevara

Demián Bichir

Character: Fidel Castro

Joaquim de Almeida

Character: President René Barrientos

Pablo Durán

Character: Pacho (Alberto Fernández Montes de Oca)

Eduard Fernández

Character: Ciro Algarañaz

Marc-André Grondin

Character: Régis Debray

Óscar Jaenada

Character: Darío (David Ardiazola)

Kahlil Méndez

Character: Urbano (Leonardo Tamayo Núñez)

Cristian Mercado

Character: Inti (Guido Peredo Liegue)

Jordi Mollà

Character: Captain Mario Vargas

Gastón Pauls

Character: Ciro Bustos

Antonio Peredo

Character: Coco (Roberto Peredo Liegue)

Jorge Perugorría

Character: Joaquin (Juan Vitalo 'Vilo' Acuña)

Lou Diamond Phillips

Character: Mario Monje

Franka Potente

Character: Tania (Haydee Tamara Bunke Bider)

Othello Rensoli

Character: Pombo (Harry Villegas Tamayo)

Armando Riesco

Character: Benigno (Dariel Alarcón Ramirez)

Néstor Rodulfo

Character: Miguel (Manuel Hernández Osorio)

Catalina Sandino Moreno

Character: Aleida March

Norman Santiago

Character: Tuma (Carlos Coello)

Rodrigo Santoro

Character: Raúl Castro

Mark Umbers

Character: George Roth

Yul Vazquez

Character: Alejandro Ramírez

María D. Sosa

Character: Aleidita

Raúl Beltrán

Character: Bolivian Customs Agent #1

Raúl 'Pitín' Gómez

Character: Bolivian Customs Agent #2

Paty M. Bellott

Character: Woman at Airport

Ezequiel Díaz

Character: Loro (Jorge Vázquez Viaña)

Juan Salinas

Character: Polo (Apolinar Aquino Quispe)

Luis Muñoz

Character: Serapio Aquino Tudela

Lorenzo Ariel Muñoz

Character: Camba (Orlando Jiménez Baznán)

Aarón Vega

Character: Ricardo (José María Martínez Tamayo)

Giraldo Moisés

Character: Braulio (Israel Reyes Zayas)

Rubén Ochandiano

Character: Rolando (Eliseo Reyes Rodriguez)

Roberto Guilhon

Character: Ernesto (Freddie Maymura Hurtado)

Carlos Acosta-Milian

Character: Antonio Domínguez Flores

Edgardo Rodríguez

Character: Arturo (René Martínez Tamayo)

José Juan Rodríguez

Character: Moro (Octavio de la Concepción y de la Pedraja)

Daniel Larrazábal

Character: Ñato (Julio Luis Méndez Korne)

Wilder Salinas

Character: Julio

Jimmy A. Céspedes

Character: Eustaquio (Lucio Edilberto Galván Hidalgo)

Eitán Vázquez

Character: Salustio Choque Choque

Oscar Aviles

Character: Pedro (Antonio Jiménez Tardio)

Ruben Salinas

Character: Paco (José Castillo Chávez)

Daniel Aguirre

Character: Aniceto Reinaga

Miguel Villarroel

Character: Carlos

Diego Ortiz

Character: Willy (Simón Cuba Saravia)

Jorge Arturo Lora

Character: Chapaco (Jaime Arana Campero)

Marisé Álvarez

Character: Vilma Espín

Eduardo Espinosa

Character: El Vallegrandino

Antonio de la Torre

Character: Lieutenant Carlos Fernández

Marco Antonio

Character: Plainclothes Policeman

Luis Bredow

Character: Honorato Rojas

María Cristina Calá

Character: Honorato's Wife

Edison Narváez

Character: Pablito (Francisco Huanca)

Bart Santana

Character: Daniel (Pastor Barrera Quintana)

Raúl Núñez

Character: Eusebio Tapia Arune

Jesús Carrillo

Character: Vicente Roeabado Terrazas

José Julio Park

Character: Chino (Juan Pablo Chang)

Juan Carlos Vellido

Character: Major Hernán Plata

Raúl Arévalo

Character: Captured Soldier #1

Daniel Holguín

Character: Captured Soldier #2

Sergio Deustua

Character: Captured Soldier #3

Tom Minder

Character: American #1

Andrew Petrotta

Character: American #2

Frederic W. Brost

Character: American #3

Geischglin Rojas

Character: Padilla

Stephen Casmier

Character: Captain Mitchell

James D. Dever

Character: Major Ralph 'Pappy' Shelton

Roberto San Martín

Character: Captain Gary Prado

Luis Callejo

Character: Bolivian Interrogator

Matt Damon

Character: Fr. Schwartz

Eduard Sanjines

Character: Reporter #1

Diego Salazar

Character: Reporter #2

René Aragón

Character: Reporter #3

Pedro Casablanc

Character: Colonel Joaquín Zenteno

Tomás del Estal

Character: General Alfredo Ovando Candía

David Zambrana

Character: Chingolo

Flavio Morales

Character: Soldier Playing Possum

José María Piñeda

Character: Hiding Soldier

Mónica Montoya

Character: Store Owner

Saúl Avila

Character: Coca Vendor

Miguel Antelo

Character: Prado's Radio Operator

David Selvas

Character: Lieutenant Colonel Andrés Selich

Jesús Carroza

Character: Eduardo

César Salgado

Character: Guard at Door

Martín Bello

Character: Bolivian Soldier

Vismark Tito Rojas

Character: Lieutenant Eduardo Huerta

Enrique Arce

Character: Lieutenant Carlos Pérez

Cristhian Esquivel

Character: Sergeant Mario Terán

Benjamín Benítez

Character: Rudolfo (uncredited)

Mariu Bárcena

Character: Embassy Girl (uncredited)

Mizan Kirby

Character: Ernesta Loud Demonstrator (uncredited)

Antonio Pardo

Character: Ranger Boliviano (uncredited)

Jason Rivera

Character: Un delegate (uncredited)

Uzimann

Character: Indian Diplomat (uncredited)

Steven Weisz

Character: News Cameraman (uncredited)