Matt Damon

Character: Spirit (voice)

James Cromwell

Character: The Colonel (voice)

Daniel Studi

Character: Little Creek (voice)

Chopper Bernet

Character: Sgt. Adams (voice)

Jeff LeBeau

Character: Murphy / Railroad Foreman (voice)

John Rubano

Character: Soldier (voice)

Richard McGonagle

Character: Bill (voice)

Matt Levin

Character: Joe (voice)

Adam Paul

Character: Pete (voice)

Robert Cait

Character: Jake (voice)

Charles Napier

Character: Roy (voice)

Meredith Wells

Character: Little Indian Girl (voice)

Zahn McClarnon

Character: Little Creek's Friend (voice)

Michael Horse

Character: Little Creek's Friend (voice)

Donald Fullilove

Character: Train Pull Foreman (voice)