Edward Norton

Character: Will Graham

Anthony Hopkins

Character: Hannibal Lecter

Ralph Fiennes

Character: Francis Dolarhyde

Emily Watson

Character: Reba McClane

Harvey Keitel

Character: Jack Crawford

Philip Seymour Hoffman

Character: Freddy Lounds

Anthony Heald

Character: Dr. Chilton

Mary-Louise Parker

Character: Molly Graham

Tyler Patrick Jones

Character: Josh Graham

Ken Leung

Character: Lloyd Bowman

Frankie Faison

Character: Barney

Lalo Schifrin

Character: Conductor

Tim Wheater

Character: Flautist

John Rubinstein

Character: Dinner Guest

David Doty

Character: Dinner Guest

Brenda Strong

Character: Dinner Guest

Robert Curtis Brown

Character: Dinner Guest

Mary Anne McGarry

Character: Dinner Guest

Marc Abraham

Character: Dinner Guest

Veronica De Laurentiis

Character: Dinner Guest

Michael Cavanaugh

Character: Forensic Dentist

Madison Mason

Character: Police Commissioner

Bill Duke

Character: Police Chief

Cliff Dorfman

Character: Cop

Phillip B. Fahey

Character: Cop

Tom Verica

Character: Charles Leeds

Marguerite MacIntyre

Character: Valerie Leeds

Thomas Curtis

Character: Billy Leeds

Azura Skye

Character: Bookseller

Jeanine Jackson

Character: Dr. Hassler

William Lucking

Character: Byron Metcalf

Katie Rich

Character: Woman Detective

Alex Berliner

Character: Photographer

Ellen Burstyn

Character: Grandma Dolarhyde (voice) (uncredited)

Mary Beth Hurt

Character: Museum Curator (uncredited)

James Pickens Jr.

Character: Male Zoo Doctor (uncredited)

Frank Whaley

Character: Ralph Mandy (uncredited)

Tanya Newbould

Character: Chromalux Secretary

Elizabeth Dennehy

Character: Beverly

Joseph Simmons

Character: Janitor

Mark Moses

Character: Father in Video

Norman Fessler

Character: Driver (uncredited)

Alex D. Linz

Character: Young Dolarhyde (voice)

Jordan Gruber

Character: Sean Leeds

Morgan Gruber

Character: Susie Leeds

Richard Pelzman

Character: Locksmith

Andreana Weiner

Character: Dr. Bloom's Secretary

Stanley Anderson

Character: Jimmy

Terence Rowley

Character: Superintendent

Gianni Russo

Character: Newsie

Al Brown

Character: Tattler Guard

Edward Nickerson

Character: FBI Agent

Kyra Helfrich

Character: Child in Video

Frank Bruynbroek

Character: Chef

Dwier Brown

Character: Mr. Jacobi

Grace Stephens

Character: Jacobi Child

Lucy Stephens

Character: Jacobi Child

Kevin Bashor

Character: Jacobi Child

Hillary Straney

Character: Museum Secretary

Christopher Curry

Character: Mr. Fisk

Conrad E. Palmisano

Character: Deputy in Car

Tony Reynolds

Character: FBI Agent