Zach Braff

Character: Chicken Little (voice)

Garry Marshall

Character: Buck Cluck (voice)

Don Knotts

Character: Mayor Turkey Lurkey (voice)

Amy Sedaris

Character: Foxy Loxy (voice)

Steve Zahn

Character: Runt of the Litter (voice)

Joan Cusack

Character: Abby Mallard (voice)

Patrick Stewart

Character: Mr. Woolensworth (voice)

Fred Willard

Character: Melvin - Alien Dad (voice)

Catherine O'Hara

Character: Tina - Alien Mom (voice)

Wallace Shawn

Character: Principal Fetchit (voice)

Harry Shearer

Character: Dog Announcer (voice)

Mark Walton

Character: Goosey Loosey (voice)

Sean Elmore

Character: Kirby - Alien Kid (voice)

Matthew Josten

Character: Kirby - Alien Kid (voice)

Evan Dunn

Character: Kirby - Alien Kid (voice)

Mark Dindal

Character: Morkubine Porcupine / Coach (voice)

Dan Molina

Character: Fish Out of Water (voice)

Patrick Warburton

Character: Alien Cop (voice)

Adam West

Character: Ace - Hollywood Chicken Little (voice)

Joe Whyte

Character: Rodriguez / Acorn Mascot / Umpire (voice)

Kelly Hoover

Character: Mama Runt (voice)

Will Finn

Character: Hollywood Fish (voice)

Dara McGarry

Character: Hollywood Abby (voice)

Mark Kennedy

Character: Hollywood Runt (voice)

Terri Douglas

Character: Additional Voices (voice)

Pat Fraley

Character: Additional Voices (voice)

Scott Menville

Character: Additional Voices (voice)

Aaron Spann

Character: Additional Voices (voice)

Nathan Kress

Character: Additional Voices (voice)

Brittney Lee Harvey

Character: Additional Voices (voice)

Chris Edgerly

Character: Additional Voices (voice)

Julianne Buescher

Character: Additional Voices (voice)

Mona Marshall

Character: Additional Voices (voice)

Eddie Frierson

Character: Additional Voices (voice)